In Gokukoku no Brynhildr, skeptical Ryouta Murakami and ambitious Kuroneko head into the wilderness determined to prove that extraterrestrial life exists. Their search ends in tragedy, leaving Ryouta critically injured and forever tied to the memory of the girl who first shared his obsession with the unknown.
Ten years later, Ryouta is a high school student who still intends to prove that aliens are real in Kuroneko's honor. His ordinary life is upended when a transfer student named Neko Kuroha arrives, startling him with her resemblance to the girl he lost and with a name that feels almost too close to be a coincidence. Neko also appears to possess supernatural powers, making her impossible to ignore.
As Ryouta grows closer to her, he is pulled into a deadly world where dangerous scientists hunt witches with magical abilities who have escaped from a secret research laboratory. Neko is one of those fugitives, and she is far from alone. With other escaped witches hiding in the shadows and their captors closing in, Ryouta is forced to protect them while uncovering the truth behind the laboratory, the people pursuing them, and the cost of power in a world that refuses to let them go.