Genshiken centers on Kanji Sasahara, a shy college freshman searching for a place to belong when he discovers the Society for the Study of Modern Visual Culture at his university, a club known as Genshiken and built around the many corners of otaku culture. His first visit goes badly when senior Harunobu Madarame challenges him, and the humiliation leaves Sasahara reluctant to admit how much he shares the club's interests. Even so, he is gradually pulled into the group's everyday rhythm of anime discussion, doujinshi reading, shop visits, and convention trips.
As Sasahara grows closer to Makoto Kousaka, a closet otaku who is far more comfortable hiding his enthusiasm than Sasahara is, the club opens into a wider college circle that also includes Kousaka's non-otaku girlfriend Saki Kasukabe, whose perspective introduces curiosity, friction, and a grounded outside view of the hobby that shapes the people around her; the steady Souichiro Tanaka, the quiet Mitsunori Kugayama, and cosplayer Kanako Oono. Across its college setting and changing membership, Genshiken uses humor, small social clashes, and affectionate detail to explore otaku life, tracing Sasahara's gradual acceptance of his own identity and the friendships that grow around shared obsessions while broadening its portrait of the people drawn into the club's world.