Nekopara centers on the warm, bustling everyday life of the Minazuki family, where human siblings Kashou and Shigure live alongside six catgirls. Hoping to build a future of his own, Kashou leaves home to open La Soleil, a patisserie that reflects his dream of making sweets for others. His plans quickly become more complicated when Chocola and Vanilla, two of the family's catgirls, secretly stow away so they can stay by his side. Together they help run the shop and welcome customers, while at home Shigure relies on Coconut, Azuki, Cinnamon, and Maple to keep the household running smoothly.
As the story follows their routines, small mishaps, and shared affection, Nekopara leans into lighthearted slice-of-life comedy and the soft, affectionate bond between humans and catgirls. The family's life becomes even livelier when they adopt Cacao, a stray kitten who adds another layer of warmth to the household. Based on the popular visual novel series, the adaptation offers a charming and relaxed portrait of family, work, and the simple joys of everyday companionship.